Essential Medicinal Chemistry of Essential Medicines
نویسندگان
چکیده
منابع مشابه
The Essential Medicinal Chemistry of Curcumin
Curcumin is a constituent (up to ∼5%) of the traditional medicine known as turmeric. Interest in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led to their extensive investigation. Curcumin has recently been classified as both a PAINS (pan-assay interference compounds) and an IMPS (invalid metabolic panaceas) candidate. The likely false activity of curcu...
متن کاملEssential medicines are still essential.
On Oct 21, WHO published the full report of the 20th Expert Committee on the Selection and Use of Essential Medicines, with its new WHO Model List of Essential Medicines (EML). The new list includes recently developed medicines for drug-resistant tuberculosis (bedaquiline and delamanid), a number of new cancer treatments (such as imatinib, rituximab, and trastuzumab), and, perhaps most controve...
متن کاملDefining fraudulent essential medicines
Many of the flows described in this study can affect grandscale geopolitical events. Cocaine trafficking has fed instability in Guinea-Bissau; firearms trafficking has fueled a rebellion in northern Mali; maritime piracy threatens to undermine commerce in the Gulf of Guinea. These flows demonstrate that transnational organized crime has truly risen to the level of a security threat in West Africa.
متن کاملThe Concept of Essential Medicines
Essential medicines are those that satisfy the priority health care needs of the population. They are selected with due regard to public health relevance, evidence on efficacy and safety, and comparative cost-effectiveness. Essential medicines are intended to be available within the context of functioning health systems at all times in adequate amounts, in the appropriate dosage forms, with ass...
متن کاملEssential medicines pricing--reform needed.
In The Lancet today, Alexandra Cameron and colleagues report on the price, availability, and relative aff ordability of a series of essential medicines in the six WHO administrative regions, in a secondary analysis of data collected in WHO/Health Action International (HAI) surveys. This new report builds on their previous work outlining drug prices in the WHO/HAI database and their relation to ...
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ژورنال
عنوان ژورنال: Journal of Medicinal Chemistry
سال: 2020
ISSN: 0022-2623,1520-4804
DOI: 10.1021/acs.jmedchem.0c00415